I have installed Intuit QuickBooks Accountant Edition 2013 in my system.
How can I integrate a QuickBooks desktop application with a asp.net application
Please check my post in the following SO thread - How to use quick book invoice api in asp.net
If you want to create non-saas custom solution, then you should use traditional QBSDK. https://developer.intuit.com/docs/0025_quickbooksapi/0055_devkits/0250_qb